Glut1 Deficiency Foundation
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About Glut1 Deficiency


Glut1 Deficiency, G1D, Glut1 DS, or De Vivo Disease
Glucose Transporter Type 1 Deficiency Syndrome is a genetic disorder that impairs brain metabolism. Glucose isn’t transported properly into the brain, leaving it starving for the energy it needs to grow and function.

Glut1 Deficiency is caused by a mutation in the SLC2A1 gene, which regulates the glucose transporter protein type 1 (Glut1).  Glut1 is the principal transporter of glucose, the primary source of energy, across the blood-brain barrier.  More than 100 different types of mutations and deletions of this gene have been found to date in Glut1 Deficiency patients.

The impaired glucose transport associated with Glut1 Deficiency causes an array of symptoms which may vary considerably from one patient to another. Some signs and symptoms may include seizures, movement disorders, speech and language disorders, and developmental delays. There are currently a few hundred patients diagnosed worldwide, but experts believe there are thousands more yet to be discovered.

There is no cure for Glut1 Deficiency.  The current standard of care treatment is a ketogenic diet, which helps improve most symptoms for most patients by giving the brain an alternate source of energy and helps optimize brain growth and development.

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Glut1 Deficiency Foundation
PO Box 737 
Owingsville, KY 40360    
​info@G1DFoundation.org

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Copyright © 2018 Glut1 Deficiency Foundation
  • Home
  • About Glut1 Deficiency
    • What is Glut1 Deficiency?
    • Key Terms in Glut1 Deficiency
    • About the Ketogenic Diet
    • Brochures
    • Professional Guide
    • Newly Diagnosed
    • Educational Video Project
    • Resources
    • Cognition and Learning
    • Related Links
    • Research News
    • Recent Publications
    • Patient Registry
    • Videos
    • Materiales en Español
    • Family Recommended Specialists >
      • Recommend a Specialist
  • About G1DF
    • About the Foundation
    • Leadership Team
    • Medical Advisory Board
    • Scientific Advisory Board
    • Educational Events and Exhibits
    • Ways to Help
    • Research Grant Program
  • News
    • Recent News
    • Foundation Newsletters >
      • Winter 2018
      • Fall 2017
      • Summer 2017
      • Spring 2017
      • Winter 2017
  • Conferences
    • Conferences
    • 2019 Conference - Washington, DC
    • Past Conferences >
      • 2017 Conference - Nashville
      • 2015 conference – Orlando
      • 2013 Conference – Houston >
        • 2013 Houston Conference Webcasts
      • 2012 Conference – Indianapolis
      • Conference Summary Reports
  • Stories
    • Stories >
      • Emily
      • Bobby
      • Lilly
      • Allison
      • Katie
      • Tessa
      • Justin
      • Whitney
      • Ryan
      • Erik
      • Pattygrace
      • Chris
      • Sam
      • Collette
      • Phil
      • Joshua
      • DeAndre
      • Matt
      • Jayden
      • Brittany
      • Macie
      • Braden
      • Dalton
      • Jordan
      • Joelle
      • Sabrina
      • Thomas
      • Haley
      • Reed
      • Ben
      • Parys
      • Ronnie-Louise
      • Colin
      • Nathan
      • Lee
      • Dominic
      • Raina
      • Dylan
      • Brayden
      • Elli
      • Jacob
      • Rian
      • Hailey
      • Olivia
      • Addie
      • Drake
    • Share Your Story
  • Get Involved
    • Ways to Give
    • Shop to Support
    • Donate
    • Sign Up for Our Mailing List
    • Love Some1 with Glut1 >
      • 2018 Love Some1
    • Fundraising >
      • Fundraising Help
  • Contact Us
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