Glut1 Deficiency Foundation
  • Home
  • About Glut1 Deficiency
    • What is Glut1 Deficiency?
    • Key Terms in Glut1 Deficiency
    • About the Ketogenic Diet
    • Newly Diagnosed
    • Research >
      • Research Compass
      • Research News
    • Patient Registry
    • Resources >
      • Resource List
      • Videos
      • The Patient Voice
      • Cognition and Learning
      • Family Recommended Specialists
      • COVID-19
      • Patient Stories >
        • Family Stories >
          • Share Your Story
      • Materiales en Español
      • Brochures
  • About G1DF
    • About the Foundation
    • Leadership Team
    • Medical Advisory Board
    • Scientific Advisory Board
    • Educational Events and Exhibits
    • Ways to Help
  • News
    • Glimpses | The G1DF Blog
    • Foundation Newsletters >
      • Summer 2022
      • Spring 2022
      • Winter 2022
      • Fall 2021
      • Summer 2021
      • Spring 2021
      • Winter 2021
      • Fall 2020
      • Summer 2020
      • Spring 2020
      • Winter 2020
      • Fall 2019
      • Summer 2019
      • Spring 2019
      • Winter 2019
      • Fall 2018
      • Summer 2018
      • Spring 2018
      • Winter 2018
      • Fall 2017
      • Summer 2017
      • Spring 2017
      • Winter 2017
  • Conferences and Events
    • 2022 Scientific and Family Conference
    • Conferences and Events
    • Glut1 Gatherings on Zoom
  • Get Involved
    • Family and Professional Networks
    • Volunteer Network
    • UTSW Surveys
    • Sign Up for Our Mailing List
    • Ways to Give
    • Shop to Support
    • Donate
    • Love Some1 with Glut1 >
      • 2022 Love Some1 with Glut1
    • Million Dollar Bike Ride
    • Fundraising >
      • Fundraising Help
      • Host a Fundraiser
  • Donate
Picture
Revised August 13, 2019

NIH Funded Research Studies

Triheptanoin (C7) treatment for Glucose transporter type 1 deficiency (G1D) with or without the ketogenic diet

(two separate studies)
Email: Rare.Diseases@UTSouthwestern.edu (physicians or patients).
Location: The University of Texas Southwestern Medical Center, Dallas, Texas.
Funding agencies: National Institute of Neurological Disorders and Stroke (National Institutes of Health)
                                   and Glut1 Deficiency Foundation
Approvals: UT Southwestern Medical Center Institutional Review Board and FDA
Principal Investigator: Juan M. Pascual, MD, PhD
 
Two NIH-funded studies are ongoing using food-grade C7 oil in G1D.

The purpose of the first study is to answer the question of whether C7 impacts neuropsychological test results (cognitive capacity, including attention, comprehension, memory, etc.) in G1D patients taking a regular diet.

​A second study (unrelated) investigates whether C7 is compatible (i.e., can be taken) with the ketogenic diet. EEG and blood work will be part of these studies.
 
Patients diagnosed by DNA testing or by PET scan will be eligible for these studies. They may not be (for the first study) but must be (for the second study) taking a ketogenic diet. No patient will be asked to or should change diets just for these studies.

  • The first study (ClinicalTrials.gov NCT03181399) lasts 9 months (6 months on C7 and then 3 months off C7) and requires three 3-day visits to Dallas over 9 months. About 24 hrs. of the 3 days will be inpatient.
 
  • For the second study (ClinicalTrials.gov NCT03301532), eligible patients will be previously receiving a ketogenic diet as part of their routine G1D management. This is a short (about 4-day) study. About two of the 4 days will be inpatient.
 
There will be no patient or medical insurance charges. Travel expenses up to $1,220 plus a $250 stipend for lost time are available upon submission of expense receipts after each visit is completed. Reimbursement is via prepaid credit card. Discounted local hotel rates are available.
 
The University of Texas Southwestern Medical Center and the NIH are non-profit institutions and hold no commercial interests in these studies.


Join OUr Networks

Picture
Picture
Picture

Picture
Picture

Glut1 Deficiency Foundation
PO Box 737 
Owingsville, KY 40360    
​info@G1DFoundation.org
​
Contact Us

​​Resources and information on this website are not intended as medical care or advice.
​​Please consult with your healthcare provider.
Picture
Mailing List
​
Shop to Support
Privacy Policy
Terms of Use

Cookie Statement
                    

Picture
Picture
Picture
Picture
Picture

Copyright © 2021 Glut1 Deficiency Foundation
  • Home
  • About Glut1 Deficiency
    • What is Glut1 Deficiency?
    • Key Terms in Glut1 Deficiency
    • About the Ketogenic Diet
    • Newly Diagnosed
    • Research >
      • Research Compass
      • Research News
    • Patient Registry
    • Resources >
      • Resource List
      • Videos
      • The Patient Voice
      • Cognition and Learning
      • Family Recommended Specialists
      • COVID-19
      • Patient Stories >
        • Family Stories >
          • Share Your Story
      • Materiales en Español
      • Brochures
  • About G1DF
    • About the Foundation
    • Leadership Team
    • Medical Advisory Board
    • Scientific Advisory Board
    • Educational Events and Exhibits
    • Ways to Help
  • News
    • Glimpses | The G1DF Blog
    • Foundation Newsletters >
      • Summer 2022
      • Spring 2022
      • Winter 2022
      • Fall 2021
      • Summer 2021
      • Spring 2021
      • Winter 2021
      • Fall 2020
      • Summer 2020
      • Spring 2020
      • Winter 2020
      • Fall 2019
      • Summer 2019
      • Spring 2019
      • Winter 2019
      • Fall 2018
      • Summer 2018
      • Spring 2018
      • Winter 2018
      • Fall 2017
      • Summer 2017
      • Spring 2017
      • Winter 2017
  • Conferences and Events
    • 2022 Scientific and Family Conference
    • Conferences and Events
    • Glut1 Gatherings on Zoom
  • Get Involved
    • Family and Professional Networks
    • Volunteer Network
    • UTSW Surveys
    • Sign Up for Our Mailing List
    • Ways to Give
    • Shop to Support
    • Donate
    • Love Some1 with Glut1 >
      • 2022 Love Some1 with Glut1
    • Million Dollar Bike Ride
    • Fundraising >
      • Fundraising Help
      • Host a Fundraiser
  • Donate